The majority of scholars are of the view that i`tikaf is a highly recommended sunnah that can be performed any time throughout the year, yet it is more desirable during the last ten days of Ramadan. Women can perform i`tikaf in the mosque, as the mosque is the best place for devotion to worship and remembrance of Allah, unlike the house which does not have the spiritual atmosphere of the mosque. Most scholars are of the view that it is not permissible for a woman to perform it in her own prayer room at home.
Allah says,
And touch them not, but be at your devotions in the mosques [i.e. while being in the state of i`tikaf]. ” (Al-Baqarah 2:187)
To know more about the ruling of i`tikaf for women at home, watch this interesting talk with Dr. Muhammad Salah.
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Source: Huda Youtube Channel.